NOLC1

Nucleolar and coiled-body phosphoprotein 1

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    Description

    NOLC1 is a protein with 73 kDa (73,603 Da - isoform 1). It is a rna binding protein and a regulator and adaptor for molecular activity and function. It is involved in the mitotic cell cycle, cell differentiation, ribosome biogenesis and anatomical structure development.

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    Categories
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    Details
    • Complete Protein Name
      Nucleolar and coiled-body phosphoprotein 1
    • Gene ID
      9221
    • Uniprot ID
      Q14978
    • Chromossomal Location
      10q24.32
    • RNA-binding protein
      Yes
    • Molecular Function
      rna binding protein; molecular adaptor activity; molecular function regulator activity
    • Used cell type
      HEK293T; iPSCs; HeLa; HepG2
    • Used Stimuli
      puromycin, thapsigargin, heat shock, sodium arsenite
    • Subcellular Localization
      nucleus; cytoplasm
    • Reference
      Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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