KEAP1

Kelch like ECH associated protein 1

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    Description

    KEAP1 is a protein with 69 kDa. It acts as an adaptor and regulator for molecular activity and transcription activity, respectively. It is involved in some biological processes such as autophagy, protein catabolism, cell differentiation and anatomical structure development.

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    Details
    • Complete Protein Name
      Kelch like ECH associated protein 1
    • Gene ID
      9817
    • Uniprot ID
      Q14145
    • Chromossomal Location
      19p13.2
    • RNA-binding protein
      No
    • Molecular Function
      molecular adaptor activity; transcription regulator activity
    • Used cell type
      HEK293T; iPSCs
    • Used Stimuli
      sodium arsenite
    • Subcellular Localization
      cytoplasm; nucleus
    • Reference
      Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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