HNRNPA1

Heterogeneous nuclear ribonucleoprotein A1

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    Description

    HnRNPA1 is a protein with 38 kDa (38,747 Da - isoform 1). It is a rna and dna binding protein. It is involved in several biological processes such as nuclecyotplasmic transport, mrna metabolic processes and telomere organization.

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    Details
    • Complete Protein Name
      Heterogeneous nuclear ribonucleoprotein A1
    • Gene ID
      3178
    • Uniprot ID
      P09651
    • Chromossomal Location
      12q13.13
    • RNA-binding protein
      Yes
    • Molecular Function
      rna binding; dna binding
    • OMIM Disease
      Amyotrophic lateral sclerosis 20; Provisional (not 100% verified): Inclusion body myopathy with early-onset Paget disease without frontotemporal dementia 3, Myopathy distal 3
    • Used cell type
      HeLa; 3T3
    • Used Stimuli
      sodium arsenite; sorbitol; oxidative, hyperosmotic and heat shock
    • Subcellular Localization
      nucleus; cytoplasm
    • Reference
      Guil S, Long JC, Cáceres JF. hnRNP A1 relocalization to the stress granules reflects a role in the stress response. Mol Cell Biol. 2006 Aug;26(15):5744-58.
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