GTF3C4

General transcription factor IIIC subunit 4

    view_headline
    Description

    GTF3C4 is a protein with almost 92 kDa (91,982 Da). It is a dna binding protein with catalytic, transferase, molecular function regulator and general transcription initiation factor activities. It is therefore involved in chromatin organization, dna-templated transcription and in trna metabolic processes.

    view_module
    Categories
    view_module
    Details
    • Complete Protein Name
      General transcription factor IIIC subunit 4
    • Gene ID
      9329
    • Uniprot ID
      Q9UKN8
    • Chromossomal Location
      9q34.13
    • RNA-binding protein
      No
    • Molecular Function
      dna binding; catalytic activity (acting on protein); transferase activity; molecular function regulator activity; general transcription initiation factor activity
    • Used cell type
      U-2 OS
    • Used Stimuli
      sodium arsenite
    • Subcellular Localization
      nucleus
    • Reference
      Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020 Dec 3;80(5):876-891.e6.
    keyboard_arrow_up