GTF3C1

General transcription factor IIIC subunit 1

GTF3C1 is a protein with 238 kDa (238,875 Da - isoform 2). It is involved in dna-templated transcription and in trna metabolic processes.

Complete Protein Name

General transcription factor IIIC subunit 1
Gene ID

2975
Uniprot ID

Q12789
Chromossomal Location

16p12.1
RNA-binding protein

No
Molecular Function

dna binding; general transcription initiation factor activity
Used cell type

U-2 OS
Used Stimuli

sodium arsenite
Subcellular Localization

nucleus
Reference

Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020 Dec 3;80(5):876-891.e6.