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    GOLGA2

    Golgin A2/Golgin subfamily A member 2

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      Description

      GOLGA2 codes for golgin A2 which is a protein with 113 kDa (113,086 Da - isoform 1). It has cytoskeletal protein binding properties since it binds some microtubule proteins. It is involved in protein glycosylation, autophagy, cytoskeleton organization, chromsome segregation, vesicle-mediated transport, assembly of protein-containing complexes, meiotic and mitotic nuclear division.

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      Details
      • Complete Protein Name
        Golgin A2/Golgin subfamily A member 2
      • Gene ID
        2801
      • Uniprot ID
        Q08379
      • Chromossomal Location
        9q34.11
      • RNA-binding protein
        No
      • Molecular Function
        cytoskeletal protein binding
      • OMIM Disease
        Developmental delay with hypotonia, myopathy, and brain abnormalities
      • Used cell type
        HEK293T, iPSCs, HeLa, HepG2
      • Used Stimuli
        sodium arsenite, puromycin, thapsigargin, heat shock
      • Subcellular Localization
        golgi apparatus, endoplasmic reticulum, cytoplasm (cytoskeleton, spindle pole)
      • Reference
        Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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