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    GIGYF2

    GRB10 interacting GYF protein 2

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      Description

      GIGYF2 is a protein with 150 kDa (150,070 Da - isoform 1). It acts as a rna binding protein and as molecular adaptor activity. It is involved in the cell mytotic cycle, immune system processes, rna metabolism, cell signalling and differentiation.

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      Details
      • Complete Protein Name
        GRB10 interacting GYF protein 2
      • Gene ID
        26058
      • Uniprot ID
        Q6Y7W6
      • Chromossomal Location
        2q37.1
      • RNA-binding protein
        Yes
      • Molecular Function
        rna binding protein; molecular adaptor activity
      • OMIM Disease
        Parkinson disease 11
      • Used cell type
        HEK293; HeLa
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        cytoplasmic stress granule; cytosol; ER; golgi apparatus membrane
      • Reference
        Youn, J.-Y., Dunham, W. H., Hong, S. J., Knight, J. D. R., Bashkurov, M., Chen, G. I., Gingras, A. C. (2018). High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies. Molecular Cell, 69(3), 517–532.e11.
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