GIGYF1

GRB10 interacting GYF protein 1

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    Description

    GIGYF1 is a protein with 114 kDa. It may act as a regulator of tyrosine kinase receptor signaling. It may increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1.

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    Categories
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    Details
    • Complete Protein Name
      GRB10 interacting GYF protein 1
    • Gene ID
      64599
    • Uniprot ID
      O75420
    • Chromossomal Location
      7q22.1
    • RNA-binding protein
      No
    • Molecular Function
      none found in uniprot
    • Used cell type
      HEK293T; iPSCs
    • Used Stimuli
      sodium arsenite
    • Subcellular Localization
      cytosol
    • Reference
      Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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