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    GIGYF1

    GRB10 interacting GYF protein 1

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      Description

      GIGYF1 is a protein with 114 kDa. It may act as a regulator of tyrosine kinase receptor signaling. It may increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1.

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      Details
      • Complete Protein Name
        GRB10 interacting GYF protein 1
      • Gene ID
        64599
      • Uniprot ID
        O75420
      • Chromossomal Location
        7q22.1
      • RNA-binding protein
        No
      • Molecular Function
        none found in uniprot
      • Used cell type
        HEK293T; iPSCs; HeLa; HepG2
      • Used Stimuli
        puromycin, thapsigargin, heat shock, sodium arsenite
      • Subcellular Localization
        cytosol
      • Reference
        Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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