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    FKBP1A

    FKBP prolyl isomerase 1A

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      Description

      FKBP1A is a protein with almost 12 kDa (11,951 Da). It has transducer, isomerase, molecular function regulator and catalytic activities. It is involved in immune, muscle and nervous system processes, protein folding, cell signaling, anatomical structure development and transmembrane transport.

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      Details
      • Complete Protein Name
        FKBP prolyl isomerase 1A
      • Gene ID
        2280
      • Uniprot ID
        P62942
      • Chromossomal Location
        20p13
      • RNA-binding protein
        No
      • Molecular Function
        transporter activity; isomerase activity; molecular transducer activity; molecular function regulator activity; catalytic activity (acting on protein)
      • Used cell type
        U-2 OS
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        sarcoplasmic reticulum membrane, cytoplasm
      • Reference
        Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020 Dec 3;80(5):876-891.e6.
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