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    EWSR1

    EWS RNA binding protein 1

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      Description

      EWSR1 is a protein with 68 kDa (68,478 Da - isoform 1). It is a rna binding protein with molecular adaptor and transcription regulator activities. It is involved in regulation of dna-templated transcription.

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      Details
      • Complete Protein Name
        EWS RNA binding protein 1
      • Gene ID
        2130
      • Uniprot ID
        Q01844
      • Chromossomal Location
        22q12.2
      • RNA-binding protein
        Yes
      • Molecular Function
        rna binding; molecular adaptor activity; transcription regulator activity
      • OMIM Disease
        Ewing sarcoma; Neuroepithelioma
      • Used cell type
        HEK293T, iPSCs, HeLa, HepG2
      • Used Stimuli
        sodium arsenite, puromycin, thapsigargin, heat shock
      • Subcellular Localization
        nucleus; cytoplasm; cell membrane
      • Reference
        Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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