ENTPD1

Ectonucleoside triphosphate diphosphohydrolase 1

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    Description

    ENTPD1 is a protein with almost 58 kDa (57,965 Da - isoform 1). It has gtpase, hydrolase and atp-dependent activties. It is involved some biological processes such as wound healing, cell adhesion and nucleobase-containing small molecule metabolic processes.

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    Details
    • Complete Protein Name
      Ectonucleoside triphosphate diphosphohydrolase 1
    • Gene ID
      953
    • Uniprot ID
      P49961
    • Chromossomal Location
      10q24.1
    • RNA-binding protein
      No
    • Molecular Function
      gtpase activity; hydrolase activity; atp-dependent activity
    • OMIM Disease
      Spastic paraplegia 64, autosomal recessive
    • Used cell type
      HEK293T; iPSCs; HeLa; HepG2
    • Used Stimuli
      sodium arsenite, puromycin, thapsigargin, heat shock
    • Subcellular Localization
      membrane
    • Reference
      Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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