ENDOV

Endonuclease V

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    Description

    ENDOV is a protein with almost 31 kDa (30,792 Da - isoform 1). It is a rna and dna binding protein with hydrolase and catalytic activities. It is involved in dna repair.

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    Categories
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    Details
    • Complete Protein Name
      Endonuclease V
    • Gene ID
      284131
    • Uniprot ID
      Q8N8Q3
    • Chromossomal Location
      17q25.3
    • RNA-binding protein
      Yes
    • Molecular Function
      dna binding; rna binding; hydrolase activity; catalytic activity (acting on rna and dna)
    • Used cell type
      T-REx 293; HeLa; HAP1
    • Used Stimuli
      sodium arsenite; nitrite
    • Subcellular Localization
      nucleus (nucleolus); cytoplasm (stress granule)
    • Reference
      Nawaz MS, Vik ES, Berges N, Fladeby C, Bjørås M, Dalhus B, Alseth I. Regulation of Human Endonuclease V Activity and Relocalization to Cytoplasmic Stress Granules. J Biol Chem. 2016 Oct 7;291(41):21786-21801.
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