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    ENC1

    Ectodermal-neural cortex 1

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      Description

      ENC1 is a protein with 66 kDa (66,130 Da - isoform 1). It is a cytoskeletal binding protein. It is invovled in cell differentiation, protein catabolic processes and anatomical structure development.

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      Details
      • Complete Protein Name
        Ectodermal-neural cortex 1
      • Gene ID
        8507
      • Uniprot ID
        O14682
      • Chromossomal Location
        5q13.3
      • RNA-binding protein
        No
      • Molecular Function
        cytoskeletal protein binding
      • Used cell type
        U-2 OS
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        nucleus matrix; cytoplasm (cytoskeleton)
      • Reference
        Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020 Dec 3;80(5):876-891.e6.
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