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    EIF5A

    Eukaryotic translation initiation factor 5A

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      Description

      EIF5A is a protein with almost 17 kDa (16,832 Da  - isoform 1). It is a rna binding protein with translation regulator activities. It is involved in regulation of dna-templated transcription, programmed cell death and signaling.

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      Details
      • Complete Protein Name
        Eukaryotic translation initiation factor 5A
      • Gene ID
        1984
      • Uniprot ID
        P63241
      • Chromossomal Location
        17p13.1
      • RNA-binding protein
        Yes
      • Molecular Function
        rna binding; translation regulator activity
      • OMIM Disease
        Faundes-Banka syndrome
      • Used cell type
        U-2 OS; RDG3; COS7
      • Used Stimuli
        sodium arsenite; heat shock; clotrimazole
      • Subcellular Localization
        nucleus; cytoplasm; endoplasmic reticulum membrane
      • Reference
        Li CH, Ohn T, Ivanov P, Tisdale S, Anderson P. eIF5A promotes translation elongation, polysome disassembly and stress granule assembly. PLoS One. 2010 Apr 1;5(4):e9942.
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