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    EIF4G3

    Eukaryotic translation initiation factor 4 gamma 3

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      Description

      EIF4G3 is a protein with 176 kDa (176,652 Da - isoform 1). It is a rna binding protein with translation regulator activities. It is involved in reproductive processes, cell differentiation and anatomical structure development.

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      Details
      • Complete Protein Name
        Eukaryotic translation initiation factor 4 gamma 3
      • Gene ID
        8672
      • Uniprot ID
        O43432
      • Chromossomal Location
        1p36.12
      • RNA-binding protein
        Yes
      • Molecular Function
        rna binding; translation regulator activity
      • Used cell type
        HEK293T, iPSCs, HeLa, HepG2
      • Used Stimuli
        puromycin, thapsigargin, heat shock, sodium arsenite
      • Subcellular Localization
        cytosol
      • Reference
        Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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