EIF2B5

Eukaryotic translation initiation factor 2B subunit epsilon

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    Description

    EIF2B5 is a protein with 80 kDa. It has gtpase, regulator and molecular function regulator activities. It is involved in cytoplasmic translations, immune system and reproductive processes, signaling, cell differentiation and anatomical structure development.

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    Tags
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    Details
    • Complete Protein Name
      Eukaryotic translation initiation factor 2B subunit epsilon
    • Gene ID
      8893
    • Uniprot ID
      Q13144
    • Chromossomal Location
      3q27.1
    • RNA-binding protein
      No
    • Molecular Function
      gtpase activity; translation regulator activity; molecular function regulator activity
    • OMIM Disease
      Leukoencephalopathy with vanishing white matter 5, with or without ovarian failure
    • Used cell type
      NIH-3T3; SVT-MEF
    • Used Stimuli
      thapsigargin
    • Subcellular Localization
      cytoplasm
    • Reference
      Kimball, S. R., Horetsky, R. L., Ron, D., Jefferson, L. S., & Harding, H. P. (2003). Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes. American Journal of Physiology-Cell Physiology, 284(2), C273–C284.
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