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    EIF2B3

    Eukaryotic translation initiation factor 2B subunit gamma

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      Description

      EIF2B3 is a protein with 50 kDa (50,240 Da - isoform 1). It has gtpase, regulator and molecular function regulator activities. It is involved in cytoplasmic translations, immune system and reproductive processes, signaling, cell differentiation and anatomical structure development.

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      Details
      • Complete Protein Name
        Eukaryotic translation initiation factor 2B subunit gamma
      • Gene ID
        8891
      • Uniprot ID
        Q9NR50
      • Chromossomal Location
        1p34.1
      • RNA-binding protein
        No
      • Molecular Function
        gtpase activity; translation regulator activity; molecular function regulator activity
      • OMIM Disease
        Leukoencephalopathy with vanishing white matter 3, with or without ovarian failure
      • Used cell type
        NIH-3T3; SVT-MEF
      • Used Stimuli
        thapsigargin
      • Subcellular Localization
        cytoplasm
      • Reference
        Kimball, S. R., Horetsky, R. L., Ron, D., Jefferson, L. S., & Harding, H. P. (2003). Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes. American Journal of Physiology-Cell Physiology, 284(2), C273–C284.
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