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    EIF2B2

    Eukaryotic translation initiation factor 2B subunit beta

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      Description

      EIF2B2 is a protein with almost 39 kDa. It has gtpase, regulator and molecular function regulator activities. It is involved in cytoplasmic translations, immune system and reproductive processes, signaling, cell differentiation and anatomical structure development.

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      Details
      • Complete Protein Name
        Eukaryotic translation initiation factor 2B subunit beta
      • Gene ID
        8892
      • Uniprot ID
        P49770
      • Chromossomal Location
        14q24.3
      • RNA-binding protein
        No
      • Molecular Function
        gtpase activity; translation regulator activity; molecular function regulator activity
      • OMIM Disease
        Leukoencephalopathy with vanishing white matter 2, with or without ovarian failure
      • Used cell type
        NIH-3T3; SVT-MEF
      • Used Stimuli
        thapsigargin
      • Subcellular Localization
        cytoplasm
      • Reference
        Kimball, S. R., Horetsky, R. L., Ron, D., Jefferson, L. S., & Harding, H. P. (2003). Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes. American Journal of Physiology-Cell Physiology, 284(2), C273–C284.
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