DNAI1

Dynein axonemal intermediate chain 1

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    Description

    DNAI1 is a protein with 79 kDa (79,283 Da - isoform 1). It has cytoskeletal motor activity. It is involved in cytoskeleton organization, microtubule-based movement, reproductive process, cell signaling, cilium organization, cell motility, anatomical structure development and assembly of protein-containing complexes.

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    Details
    • Complete Protein Name
      Dynein axonemal intermediate chain 1
    • Gene ID
      27019
    • Uniprot ID
      Q9UI46
    • Chromossomal Location
      9p13.3
    • RNA-binding protein
      No
    • Molecular Function
      cytoskeletal motor activity
    • OMIM Disease
      Ciliary dyskinesia, primary, 1, with or without situs inversus
    • Used cell type
      COS-7; NIH3T3
    • Used Stimuli
      sodium arsenite; cycloheximide; puromycin
    • Subcellular Localization
      cytoplasm (cytoskeleton, cilium axoneme); dynein axonemal particle
    • Reference
      Loschi M, Leishman CC, Berardone N, Boccaccio GL. Dynein and kinesin regulate stress-granule and P-body dynamics. J Cell Sci. 2009 Nov 1;122(Pt 21):3973-82.
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