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    DIDO1

    Death inducer-obliterator 1

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      Description

      DIDO1 is a protein with almost 244 kDa (243,873 Da - isoform 4). It is a rna binding protein. It is involved in dna-templated transcription, programmed cell death and cell signaling.

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      Details
      • Complete Protein Name
        Death inducer-obliterator 1
      • Gene ID
        11083
      • Uniprot ID
        Q9BTC0
      • Chromossomal Location
        20q13.33
      • RNA-binding protein
        Yes
      • Molecular Function
        rna binding
      • Used cell type
        U-2 OS
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        nucleus; cytoplasm (spindle, cytoskeleton)
      • Reference
        Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020 Dec 3;80(5):876-891.e6.
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