DHX33

DEAH-box helicase 33

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    Description

    DHX33 is a protein with almost 79 kDa (78,874 Da - isoform 1). It is a dna and rna binding protein and has hydrolase, catalytic and transcription regulator activities. It is involved in immune system responses, regulation of dna-templated transcription, cell signaling and assembly of protein-containing complexes.

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    Details
    • Complete Protein Name
      DEAH-box helicase 33
    • Gene ID
      56919
    • Uniprot ID
      Q9H6R0
    • Chromossomal Location
      17p13.2
    • RNA-binding protein
      Yes
    • Molecular Function
      dna binding; rna binding; catalytic activity; hydrolase activity; transcription regulator activity
    • Used cell type
      HEK293T, iPSCs, HeLa, HepG2
    • Used Stimuli
      puromycin, thapsigargin, heat shock, sodium arsenite
    • Subcellular Localization
      nucleus (nucleolus, nucleoplasm); cytoplasm
    • Reference
      Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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