menu
Explore the database
search
search
    close

    CNOT8

    CCR4-NOT transcription complex subunit 8

      view_headline
      Description

      CNOT8 codes for CCR4-NOT transcription complex subunit 8 which is a protein with 33 kDa (33,540 Da - isoform 1). It is a rna binding protein with hydrolase and catalytic activities. It is involved in mrna metabolic processes and silencing of regulatory ncrna-mediated genes.

      view_module
      Categories
      view_module
      Tags
      view_module
      Details
      • Complete Protein Name
        CCR4-NOT transcription complex subunit 8
      • Gene ID
        9337
      • Uniprot ID
        Q9UFF9
      • Chromossomal Location
        5q33.2
      • RNA-binding protein
        Yes
      • Molecular Function
        rna binding; hydrolase activity; catalytic activity (acting on rna)
      • Used cell type
        HEK293T; HeLa
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        nucleus, cytoplasm
      • Reference
        Youn, J.-Y., Dunham, W. H., Hong, S. J., Knight, J. D. R., Bashkurov, M., Chen, G. I., … Gingras, A.-C. (2018). High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies. Molecular Cell, 69(3), 517–532.e11.
      keyboard_arrow_up