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    CNOT3

    CCR4-NOT transcription complex subunit 3

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      Description

      CNOT3 codes for CCR4-NOT transcription complex subunit 3 which is a protein with almost 82 kDa (81,872 Da). It is involved in regulation of DNA-templated transcription, mrna metabolic processes, cell differentiation, silencing of regulatory ncRNA-mediated genes and anatomical structure development.

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      Details
      • Complete Protein Name
        CCR4-NOT transcription complex subunit 3
      • Gene ID
        4849
      • Uniprot ID
        O75175
      • Chromossomal Location
        19q13.42
      • RNA-binding protein
        No
      • Molecular Function
        none (according to uniprot)
      • OMIM Disease
        Intellectual developmental disorder with speech delay, autism, and dysmorphic facies
      • Used cell type
        HEK293T; HeLa
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        cytoplasm (p-body); nucleus
      • Reference
        Youn, J.-Y., Dunham, W. H., Hong, S. J., Knight, J. D. R., Bashkurov, M., Chen, G. I., … Gingras, A.-C. (2018). High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies. Molecular Cell, 69(3), 517–532.e11.
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