CLPP

Caseinolytic mitochondrial matrix peptidase proteolytic subunit

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    Description

    CLPP is a protein with 30 kDa. It has hydrolase, catalytic and atp-depend activities. It is involved in mitochondrion organization and protein catabolic processes.

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    Details
    • Complete Protein Name
      Caseinolytic mitochondrial matrix peptidase proteolytic subunit
    • Gene ID
      8192
    • Uniprot ID
      Q16740
    • Chromossomal Location
      19p13.3
    • RNA-binding protein
      No
    • Molecular Function
      hydrolase activity; catalytic activity; atp-depend activity
    • OMIM Disease
      Perrault syndrome 3
    • Used cell type
      HEK293T, iPSCs, HeLa, HepG2
    • Used Stimuli
      puromycin, thapsigargin, heat shock, sodium arsenite
    • Subcellular Localization
      mitochondrion matrix
    • Reference
      Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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