menu
Explore the database
search
search
    close

    CENPF

    Centromere protein F

      view_headline
      Description

      CENPF is a protein with 357 kDa. It is a cytoskeletal binding protein and is involved in the mitotic cell cycle, mitotic nuclear division, regulation of dna-templated transcription, chromosome seggregation, cell signaling and differentiation, anatomical structure development and assembly of protein-containing complexes.

      view_module
      Categories
      view_module
      Tags
      view_module
      Details
      • Complete Protein Name
        Centromere protein F
      • Gene ID
        1063
      • Uniprot ID
        P49454
      • Chromossomal Location
        1q41
      • RNA-binding protein
        No
      • Molecular Function
        cytoskeletal protein binding
      • OMIM Disease
        Stromme syndrome
      • Used cell type
        U-2 OS cells
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        nucleus; perinuclear region; cytoplasm (cytoskeleton, spindle)
      • Reference
        Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020 Dec 3;80(5):876-891.e6.
      keyboard_arrow_up