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    CAPZB

    Capping actin protein of muscle Z-line subunit beta

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      Description

      CAPZB is a protein with 30 kDa (30,629 Da - isoform 2). It is a cytoskeleton binding protein. It is involved in cytoskeleton organization, anatomical structure development and assembly of protein-containing complexes.

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      Details
      • Complete Protein Name
        Capping actin protein of muscle Z-line subunit beta
      • Gene ID
        832
      • Uniprot ID
        P47756
      • Chromossomal Location
        1p36.13
      • RNA-binding protein
        No
      • Molecular Function
        cytoskeletal protein binding
      • Used cell type
        U-2 OS cells
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        cytoplasm: cytoskeleton; sarcomere
      • Reference
        Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020 Dec 3;80(5):876-891.e6.
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