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    CAMSAP1

    Calmodulin regulated spectrin associated protein 1

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      Description

      CAMSAP1 is a protein with almost 178 kDa (177,972 Da - isoform 1). It is a cytoskeletal binding protein and is involved in cytoskeleton organization, cell differentiation, anatomical structure development and assembly of protein-containing complexes.

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      Details
      • Complete Protein Name
        Calmodulin regulated spectrin associated protein 1
      • Gene ID
        157922
      • Uniprot ID
        Q5T5Y3
      • Chromossomal Location
        9q34.3
      • RNA-binding protein
        No
      • Molecular Function
        cytoskeletal protein binding
      • OMIM Disease
        Cortical dysplasia, complex, with other brain malformations 12
      • Used cell type
        U-2 OS cells
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        cytoplasm: cytoskeleton
      • Reference
        Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020 Dec 3;80(5):876-891.e6.
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