BCLAF1

BCL2 associated transcription factor 1

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    Description

    BCLAF1 is a protein with 106 kDa (106,122 Da - isoform 1). It is a rna and dna binding protein and has molecular adaptor and transcription regulator activities. It is involved in regulation of dna-templated transcription, programmed cell death and signaling.

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    Categories
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    Details
    • Complete Protein Name
      BCL2 associated transcription factor 1
    • Gene ID
      9774
    • Uniprot ID
      Q9NYF8
    • Chromossomal Location
      6q23.3
    • RNA-binding protein
      Yes
    • Molecular Function
      rna binding; dna binding; molecular adaptor activity; transcription regulator activity
    • Used cell type
      HEK293T; iPSCs
    • Used Stimuli
      sodium arsenite
    • Subcellular Localization
      nucleus; nucleus speckle; cytoplasm
    • Reference
      Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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