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    BCLAF1

    BCL2 associated transcription factor 1

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      Description

      BCLAF1 is a protein with 106 kDa (106,122 Da - isoform 1). It is a rna and dna binding protein and has molecular adaptor and transcription regulator activities. It is involved in regulation of dna-templated transcription, programmed cell death and signaling.

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      Details
      • Complete Protein Name
        BCL2 associated transcription factor 1
      • Gene ID
        9774
      • Uniprot ID
        Q9NYF8
      • Chromossomal Location
        6q23.3
      • RNA-binding protein
        Yes
      • Molecular Function
        rna binding; dna binding; molecular adaptor activity; transcription regulator activity
      • Used cell type
        HEK293T; iPSCs; HeLa; HepG2
      • Used Stimuli
        puromycin, thapsigargin, heat shock, sodium arsenite
      • Subcellular Localization
        nucleus; nucleus speckle; cytoplasm
      • Reference
        Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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