BCCIP

BRCA2 and CDKN1A interacting protein

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    Description

    BCCIP is a protein with almost 36 kDa (35,979 Da - isoform 1). It is a rna binding protein, cytoskeletal binding protein, has transferase activity, regulates molecular function and has protein catalytic activity. It is involved in the mitotic cell cycle and mitotic nuclear division, dna repair, cytoskeleton organization, chromosome segregation, cell differentiation and anatomical structure development.

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    Categories
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    Details
    • Complete Protein Name
      BRCA2 and CDKN1A interacting protein
    • Gene ID
      56647
    • Uniprot ID
      Q9P287
    • Chromossomal Location
      10q26.2
    • RNA-binding protein
      Yes
    • Molecular Function
      rna binding; cytoskeletal protein binding; transferase activity; molecular function regulator activity; catalytic activity (acting on protein)
    • Used cell type
      HEK293T; iPSCs
    • Used Stimuli
      sodium arsenite
    • Subcellular Localization
      nucleus; cytoplasm
    • Reference
      Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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