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    BCCIP

    BRCA2 and CDKN1A interacting protein

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      Description

      BCCIP is a protein with almost 36 kDa (35,979 Da - isoform 1). It is a rna binding protein, cytoskeletal binding protein, has transferase activity, regulates molecular function and has protein catalytic activity. It is involved in the mitotic cell cycle and mitotic nuclear division, dna repair, cytoskeleton organization, chromosome segregation, cell differentiation and anatomical structure development.

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      Details
      • Complete Protein Name
        BRCA2 and CDKN1A interacting protein
      • Gene ID
        56647
      • Uniprot ID
        Q9P287
      • Chromossomal Location
        10q26.2
      • RNA-binding protein
        Yes
      • Molecular Function
        rna binding; cytoskeletal protein binding; transferase activity; molecular function regulator activity; catalytic activity (acting on protein)
      • Used cell type
        HEK293T; iPSCs; HeLa; HepG2
      • Used Stimuli
        puromycin, thapsigargin, heat shock, sodium arsenite
      • Subcellular Localization
        nucleus; cytoplasm
      • Reference
        Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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