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    BAZ2A

    Bromodomain adjacent to zinc finger domain 2A

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      Description

      BAZ2A is a protein with 211 kDa (211,198 Da - isoform 1). It is a dna and rna binding protein which can bind to histones aswell. It is involved in chromatin organization, dna-templated transcription and assembly of protein-containing complexes.

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      Details
      • Complete Protein Name
        Bromodomain adjacent to zinc finger domain 2A
      • Gene ID
        11176
      • Uniprot ID
        Q9UIF9
      • Chromossomal Location
        12q13.3
      • RNA-binding protein
        Yes
      • Molecular Function
        dna binding; rna binding; histone binding
      • Used cell type
        U-S OS cells
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        nucleus
      • Reference
        Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020 Dec 3;80(5):876-891.e6.
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