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    ASCC3

    Activating signal cointegrator 1 complex subunit 3

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      Description

      ASCC3 is a protein with 251 kDa (251,460 Da - isoform 1). It is a rna binding protein and has hydrolase and catalytic activity. It is involved in dna repair and protein catabolic processes.

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      Details
      • Complete Protein Name
        Activating signal cointegrator 1 complex subunit 3
      • Gene ID
        10973
      • Uniprot ID
        Q8N3C0
      • Chromossomal Location
        6q16.3
      • RNA-binding protein
        Yes
      • Molecular Function
        rna binding; hydrolase activity; catalytic activity (acting on dna)
      • OMIM Disease
        Intellectual developmental disorder, autosomal recessive 81
      • Used cell type
        HEK293T; HeLa
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        nucleus; nucleus speckle; cytoplasm
      • Reference
        Youn, J.-Y., Dunham, W. H., Hong, S. J., Knight, J. D. R., Bashkurov, M., Chen, G. I., … Gingras, A.-C. (2018). High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies. Molecular Cell, 69(3), 517–532.e11.
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