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    ARID2

    AT-rich interaction domain 2

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      Description

      ARID2 is a protein with 197 kDa (197,391 Da). It is involved in dna binding mechanisms and other processes in the cell nucleus, such as: mitotic cell cycle, dna repair, transcription, dna recombination, chromatin organization and chromosome segregation. Also has roles in immune system processes and cell adhesion.

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      Details
      • Complete Protein Name
        AT-rich interaction domain 2
      • Gene ID
        196528
      • Uniprot ID
        Q68CP9
      • Chromossomal Location
        12q12
      • RNA-binding protein
        No
      • Molecular Function
        dna binding
      • OMIM Disease
        Coffin-Siris syndrome 6
      • Used cell type
        U-2 OS cells
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        nucleus
      • Reference
        Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020 Dec 3;80(5):876-891.e6.
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