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    ANKRD17

    Ankyrin repeat domain 17

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      Description

      ANKRD17 is a protein with 274 kDa (274,258 Da). Plays important roles in cell cycle and DNA regulation: dna replication. Involved in cell signaling and differentiation. Involved in innate immune defense and in innate antibacterial immune pathways too. Target of enterovirus 71.

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      Details
      • Complete Protein Name
        Ankyrin repeat domain 17
      • Gene ID
        26057
      • Uniprot ID
        O75179
      • Chromossomal Location
        4q13.3
      • RNA-binding protein
        Yes
      • Molecular Function
        RNA binding
      • OMIM Disease
        Chopra-Amiel-Gordon syndrome
      • Used cell type
        HEK293; HeLa
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        cytoplasm, nucleus
      • Reference
        Youn, J.-Y., Dunham, W. H., Hong, S. J., Knight, J. D. R., Bashkurov, M., Chen, G. I., … Gingras, A.-C. (2018). High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies. Molecular Cell, 69(3), 517–532.e11.
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