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    ALPK2

    Alpha-protein kinase 2

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      Description

      ALPK2 is a protein with 237 kDa. It is involved in molecular mechanisms such as transferase activity and catalytic activity, acting on protein. It is involved in several biological processes such as cell signalling and differentiation, cell programmed death, establishment and maintenence of cell polarity and anatomical structure development.

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      Details
      • Complete Protein Name
        Alpha-protein kinase 2
      • Gene ID
        115701
      • Uniprot ID
        Q86TB3
      • Chromossomal Location
        18q21.31-q21.32
      • RNA-binding protein
        No
      • Molecular Function
        transferase and catalytic activity
      • Used cell type
        U-2 OS cells
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        basolateral cell membrane
      • Reference
        Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020 Dec 3;80(5):876-891.e6.
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