ADD1

Adducin 1

    view_headline
    Description

    ADD1 is a protein with 80 kDa (80,955 Da - isoform 1). It is a rna and a cytoskeleton binding protein. It is involved in cytoskeleton organization, cell differentiation, cell junction organization, anatomical structure development and assembly of protein-containing complexes.

    view_module
    Details
    • Complete Protein Name
      Adducin 1
    • Gene ID
      118
    • Uniprot ID
      P35611
    • Chromossomal Location
      4p16.3
    • RNA-binding protein
      Yes
    • Molecular Function
      rna binding; cytoskeletal protein binding
    • OMIM Disease
      Hypertension, essential, salt-sensitive
    • Used cell type
      HEK293T; iPSCs
    • Used Stimuli
      sodium arsenite
    • Subcellular Localization
      cytoskeleton; cell membrane
    • Reference
      Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
    keyboard_arrow_up