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    ADD1

    Adducin 1

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      Description

      ADD1 is a protein with 80 kDa (80,955 Da - isoform 1). It is a rna and a cytoskeleton binding protein. It is involved in cytoskeleton organization, cell differentiation, cell junction organization, anatomical structure development and assembly of protein-containing complexes.

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      Details
      • Complete Protein Name
        Adducin 1
      • Gene ID
        118
      • Uniprot ID
        P35611
      • Chromossomal Location
        4p16.3
      • RNA-binding protein
        Yes
      • Molecular Function
        rna binding; cytoskeletal protein binding
      • OMIM Disease
        Hypertension, essential, salt-sensitive
      • Used cell type
        HEK293T; iPSCs; HeLa; HepG2
      • Used Stimuli
        puromycin, thapsigargin, heat shock, sodium arsenite
      • Subcellular Localization
        cytoskeleton; cell membrane
      • Reference
        Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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