BRF1 is a protein with 73 kDa. Has various molecular functions, such as metal ion binding. Is involved in several biological processes, including rRNA transcription.
Metal ion binding ,TBP-class protein binding ,TFIIIB-type transcription factor activity
OMIM Disease
Cerebellofaciodental syndrome
Used cell type
COS7, DU145, HeLa, RAW 264.7
Used Stimuli
Sodium arsenite
Subcellular Localization
Nucleus
Reference
Stoecklin, G., Stubbs, T., Kedersha, N., Wax, S., Rigby, W. F., Blackwell, T. K., & Anderson, P. (2004). MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay. The EMBO Journal, 23(6), 1313–1324