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Description
TRAF2 is a protein with 55 kDa. Has various molecular functions, such as CD40 receptor binding. Is involved in several biological processes, including cellular response to nitric oxide.
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Categories
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Details
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Complete Protein NameTNF receptor-associated factor 2
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Gene ID7186
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Uniprot IDQ12933
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Chromossomal Location9q34.3
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RNA-binding proteinNo
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Molecular FunctionCD40 receptor binding ,enzyme binding ,identical protein binding ,mitogen-activated protein kinase kinase kinase binding ,protein complex binding ,protein kinase binding ,protein phosphatase binding ,signal transducer activity ,sphingolipid binding ,thioesterase binding ,tumor necrosis factor receptor binding ,ubiquitin protein ligase binding ,ubiquitin-protein transferase activity ,zinc ion binding
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Used cell type293T, HeLa, COS-7
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Used StimuliHeat shock
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Subcellular LocalizationCytoplasm
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ReferenceKim, W. J.; Back, S. H.; Kim, V.; Ryu, I.; Jang, S. K. (2005). Sequestration of TRAF2 into Stress Granules Interrupts Tumor Necrosis Factor Signaling under Stress Conditions. Molecular and Cellular Biology, 25(6), 2450–2462