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    TIA-1

    T-cell intracellular antigen-1

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      Description

      TIA1 is a protein with 42 kDa. Has various molecular functions, such as RNA binding. Is involved in several biological processes, including apoptotic process.

       

       

       

       

       

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      Details
      • Complete Protein Name
        T-cell intracellular antigen-1
      • Gene ID
        7072
      • Uniprot ID
        P31483
      • Chromossomal Location
        2p13.3
      • RNA-binding protein
        Yes
      • Molecular Function
        AU-rich element binding ,poly(A) binding ,RNA binding
      • OMIM Disease
        Welander distal myopathy
      • Used cell type
        DU145, COS-7, HeLa
      • Used Stimuli
        Sodium arsenite, heat shock, sorbitol, UV irradiation
      • Subcellular Localization
        Nucleus
      • Reference
        Kedersha, N. L.; Gupta, M.; Li, W.; Miller, I.; Anderson, P. (1999). RNA-Binding Proteins Tia-1 and Tiar Link the Phosphorylation of Eif-2α to the Assembly of Mammalian Stress Granules. The Journal of Cell Biology, 147(7), 1431–1442
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