Syk

Tyrosine-protein kinase SYK

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    Description

    Syk is a non-receptor tyrosine kinase with 72 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including angiogenesis.

     

     

     

     

     

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    Categories
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    Details
    • Complete Protein Name
      Tyrosine-protein kinase SYK
    • Gene ID
      6850
    • Uniprot ID
      P43405
    • Chromossomal Location
      9q22.2
    • RNA-binding protein
      No
    • Molecular Function
      ATP binding ,integrin binding ,non-membrane spanning protein tyrosine kinase activity ,phosphatase binding phosphotyrosine residue binding ,protein kinase activity ,protein kinase binding ,protein serine/threonine kinase activity ,protein tyrosine kinase activity ,SH2 domain binding ,signal transducer, downstream of receptor, with protein tyrosine kinase activity ,Toll-like receptor binding
    • Used cell type
      HEK293T, MCF7, DG75, MCF7-BD
    • Used Stimuli
      Sodium arsenite, MG132
    • Subcellular Localization
      Cytosol, Cell membrane
    • Reference
      Krisenko, M. O.; Higgins, R. L.; Ghosh, S.; Zhou, Q.; Trybula, J. S.; Wang, W.-H.; Geahlen, R. L. (2015). Syk Is Recruited to Stress Granules and Promotes Their Clearance through Autophagy. The Journal of Biological Chemistry, 290(46), 27803–27815
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