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    NONO

    Non-POU domain-containing octamer-binding protein

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      Description

      NONO is a DNA- and RNA binding protein with 54 kDa. Has various molecular functions, such as chromatin binding. Is involved in several biological processes, including DNA repair.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Non-POU domain-containing octamer-binding protein
      • Gene ID
        4841
      • Uniprot ID
        Q15233
      • Chromossomal Location
        Xq13.1
      • RNA-binding protein
        Yes
      • Molecular Function
        Chromatin binding ,core promoter binding ,identical protein binding ,RNA binding ,RNA polymerase II distal enhancer sequence-specific DNA binding ,transcription regulatory region sequence-specific DNA binding
      • OMIM Disease
        Mental retardation
      • Used cell type
        U-2 OS
      • Used Stimuli
        Sodium arsenite
      • Subcellular Localization
        Nucleus
      • Reference
        Jain,S.; Wheeler,J.; Walters,R.; Agrawal,A.; Barsic,A.; Parker,R. (2016). ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell , Volume 164 , Issue 3 , 487 – 498
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