DDX58 is an innate immune receptor with 106 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including detection of virus.
ATP binding ,double-stranded DNA binding ,double-stranded RNA binding ,helicase activity ,identical protein binding ,single-stranded RNA binding ,ubiquitin protein ligase binding ,zinc ion binding
Onomoto, K.; Jogi, M.; Yoo, JS.; Narita, R.; Morimoto, S.; Takemura, A.; Sambhara, S.; Kawaguchi, A.; Osari, S.; Nagata, K.; Matsumiya, T.; Namiki, H.; Yoneyama, M.; Fujita, T. (2012). Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity. PLoS One. 7(8):e43031