RAPTOR is a protein with 149 kDa. Has various molecular functions, such as 14-3-3 protein binding. Is involved in several biological processes, including cell cycle arrest.
14-3-3 protein binding ,protein binding, bridging ,protein complex binding ,protein kinase activator activity ,protein kinase binding ,protein serine/threonine kinase inhibitor activity, RNA polymerase III type 1 promoter DNA binding ,RNA polymerase III type 2 promoter DNA binding ,RNA polymerase III type 3 promoter DNA binding ,TFIIIC-class transcription factor binding
Used cell type
HeLa, U-2 OS, A431, MEFs
Used Stimuli
Sodium arsenite, sorbitol
Subcellular Localization
Lysosome, Cytoplasm, Cytoplasmic granule
Reference
Wippich, F.; Bodenmiller, B.; Trajkovska, M. G.; Wanka, S.; Aebersold, R.; Pelkmans, L. (2013). Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling. Cell. 152(4):791-805