menu
Explore the database
search
search
    close

    PKP1

    Plakophilin-1

      view_headline
      Description

      PKP1 is a protein with 82 kDa. Has various molecular functions, such as lamin binding. Is involved in several biological processes, including cell adhesion.

       

       

       

       

       

      view_module
      Categories
      view_module
      Tags
      view_module
      Details
      • Complete Protein Name
        Plakophilin-1
      • Gene ID
        5317
      • Uniprot ID
        Q13835
      • Chromossomal Location
        1q32.1
      • RNA-binding protein
        No
      • Molecular Function
        Intermediate filament binding ,lamin binding , signal transducer activity ,structural constituent of epidermis
      • OMIM Disease
        Ectodermal dysplasia/skin fragility syndrome
      • Used cell type
        HaCaT, MCF-7, CaCo2
      • Used Stimuli
        Heat shock, sodium arsenite
      • Subcellular Localization
        Nucleus, desmosome
      • Reference
        Hofmann, I.; Casella, M.; Schnölzer, M.; Schlechter, T.; Spring, H.; Franke, WW. (2006). Identification of the Junctional Plaque Protein Plakophilin 3 in Cytoplasmic Particles Containing RNA-binding Proteins and the Recruitment of Plakophilins 1 and 3 to Stress Granules. Mol Biol Cell. 17(3): 1388–1398
      keyboard_arrow_up