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    PABP1

    Polyadenylate-binding protein 1

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      Description

      PABP1 is a protein with 70 kDa. Has various molecular functions, such as RNA binding. Is involved in several biological processes, including gene silencing by RNA.

       

       

       

       

       

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      Details
      • Complete Protein Name
        Polyadenylate-binding protein 1
      • Gene ID
        26986
      • Uniprot ID
        P11940
      • Chromossomal Location
        8q22.3
      • RNA-binding protein
        Yes
      • Molecular Function
        mRNA 3'-UTR binding ,poly(A) binding ,poly(U) RNA binding ,protein C-terminus binding ,RNA binding ,translation activator activity
      • Used cell type
        DU145, COS-7
      • Used Stimuli
        Heat shock, UV, sodium arsenite
      • Subcellular Localization
        Nucleus, Cytoplasm
      • Reference
        Kedersha, NL.; Gupta, M.; Li, W.; Miller, I.; Anderson, P. (1999). RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules. J Cell Biol. 147(7):1431-42
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