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Description
EIF4G1 is a protein with 175 kDa. Has various molecular functions, such as ATP binding. Is involved in several biological processes, including developmental process.
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Categories
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Details
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Complete Protein NameEukaryotic translation initiation factor 4 gamma 1
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Gene ID1981
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Uniprot IDQ04637
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Chromossomal Location3q27.1
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RNA-binding proteinYes
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Molecular FunctionATP binding ,cadherin binding ,eukaryotic initiation factor 4E binding ,mRNA binding ,protein complex scaffold activity , RNA binding ,translation factor activity, RNA binding ,translation initiation factor activity ,translation initiation factor binding
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OMIM DiseaseParkinson disease
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Used cell typeCOS-7, DU145
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Used StimuliSodium arsenite
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Subcellular LocalizationCytosol, Nucleus, cytoplasm, eukaryotic translation initiation factor 4F complex, membrane, polysome
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ReferenceKedersha N., Chen S., Gilks N., Li W., Miller IJ., Stahl J., Anderson P.(2002). Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules. Mol Biol Cell. 2002 Jan;13(1):195-210