HSPB1 is a small heat shock protein with 22 kDa. Has various molecular functions, such as protein kinase binding. Is involved in several biological processes, including positive regulation of angiogenesis.
Identical protein binding ,protein binding involved in protein folding ,protein homodimerization activity ,protein kinase binding ,protein kinase C binding ,protein kinase C inhibitor activity ,RNA binding ,ubiquitin binding
OMIM Disease
Charcot-Marie-Tooth disease, Neuropathy
Used cell type
HeLa
Used Stimuli
Heat shock
Subcellular Localization
Cytoskeleton, Nucleus, Cytoplasm
Reference
Arrigo, A. P.; Suhan, J. P;, Welch, W. J. (1988). Dynamic changes in the structure and intracellular locale of the mammalian low-molecular-weight heat shock protein. Molecular and Cellular Biology, 8(12), 5059–5071