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    OASL

    2'-5'-oligoadenylate synthetase like

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      Description

      OASL is a protein with a 59 kDa (59,226 - isoform 1). It acts as a rna and dna binding protein and is involved in transferase activity. There is evidence of the involvement of OASL in immune processes and defense and cell signaling.

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      Details
      • Complete Protein Name
        2'-5'-oligoadenylate synthetase like
      • Gene ID
        8638
      • Uniprot ID
        Q15646
      • Chromossomal Location
        12q24.31
      • RNA-binding protein
        Yes
      • Molecular Function
        dna binding; rna binding; transferase activity
      • Used cell type
        NIH-3T3
      • Used Stimuli
        poly(I:C); Pam3CSK4; poly(dA:dT); 5′ppp-dsRNA
      • Subcellular Localization
        nucleus; cytoplasm
      • Reference
        Kang JS, Hwang YS, Kim LK, Lee S, Lee WB, Kim-Ha J, Kim YJ. OASL1 Traps Viral RNAs in Stress Granules to Promote Antiviral Responses. Mol Cells. 2018 Mar 31;41(3):214-223.
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