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    FAM168B

    Family with sequence similarity 168 member B

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      Description

      FAM168B is a protein with 20 kDa (20,324 Da - isoform 1). It acts as an Inhibitor of neuronal axonal outgrowth. It is a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2 and CDC27. Found in P-bodies.

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      Details
      • Complete Protein Name
        Family with sequence similarity 168 member B
      • Gene ID
        130074
      • Uniprot ID
        A1KXE4
      • Chromossomal Location
        2q21.1
      • RNA-binding protein
        No
      • Molecular Function
        none
      • Used cell type
        HEK293T; iPSCs; HeLa; HepG2
      • Used Stimuli
        puromycin, thapsigargin, heat shock, sodium arsenite
      • Subcellular Localization
        cytoplasm (perinuclear region); cell membrane; axon
      • Reference
        Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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