FAM168B

Family with sequence similarity 168 member B

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    Description

    FAM168B is a protein with 20 kDa (20,324 Da - isoform 1). It acts as an Inhibitor of neuronal axonal outgrowth. It is a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2 and CDC27. Found in P-bodies.

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    Categories
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    Details
    • Complete Protein Name
      Family with sequence similarity 168 member B
    • Gene ID
      130074
    • Uniprot ID
      A1KXE4
    • Chromossomal Location
      2q21.1
    • RNA-binding protein
      No
    • Molecular Function
      none
    • Used cell type
      HEK293T; iPSCs
    • Used Stimuli
      sodium arsenite
    • Subcellular Localization
      cytoplasm (perinuclear region); cell membrane; axon
    • Reference
      Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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