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    DDX31

    DEAD-box helicase 31

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      Description

      DDX31 is a protein with 94 kDa (94,087 Da - isoform 1). It is a rna binding protein with hydrolase and catalytic activities. It is involved in ribosome biogenesis.

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      Details
      • Complete Protein Name
        DEAD-box helicase 31
      • Gene ID
        64794
      • Uniprot ID
        Q9H8H2
      • Chromossomal Location
        9q34.13
      • RNA-binding protein
        Yes
      • Molecular Function
        rna binding; hydrolase activity; catalytic activity (acting on rna)
      • Used cell type
        U-2 OS
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        nucleus (nucleolus)
      • Reference
        Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020 Dec 3;80(5):876-891.e6.
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