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    CROCC

    Ciliary rootlet coiled-coil, rootletin

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      Description

      CROCC is a protein with 228 kDa (228,424 Da - isoform 1). It has structure molecule activity along with binding capabilities to cytoskeletal proteins. It is involved in cytoskeleton and cilium organization.

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      Details
      • Complete Protein Name
        Ciliary rootlet coiled-coil, rootletin
      • Gene ID
        9696
      • Uniprot ID
        Q5TZA2
      • Chromossomal Location
        1p36.13
      • RNA-binding protein
        No
      • Molecular Function
        structure molecule activity; cytoskeletal protein binding
      • Used cell type
        HEK293T, iPSCs, HeLa, HepG2
      • Used Stimuli
        puromycin, thapsigargin, heat shock, sodium arsenite
      • Subcellular Localization
        cytoplasm (cytoskeleton, cilium basal body, centrosome)
      • Reference
        Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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