CROCC

Ciliary rootlet coiled-coil, rootletin

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    Description

    CROCC is a protein with 228 kDa (228,424 Da - isoform 1). It has structure molecule activity along with binding capabilities to cytoskeletal proteins. It is involved in cytoskeleton and cilium organization.

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    Categories
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    Details
    • Complete Protein Name
      Ciliary rootlet coiled-coil, rootletin
    • Gene ID
      9696
    • Uniprot ID
      Q5TZA2
    • Chromossomal Location
      1p36.13
    • RNA-binding protein
      No
    • Molecular Function
      structure molecule activity; cytoskeletal protein binding
    • Used cell type
      HEK293T; iPSCs
    • Used Stimuli
      sodium arsenite
    • Subcellular Localization
      cytoplasm (cytoskeleton, cilium basal body, centrosome)
    • Reference
      Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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